Pathophysiology and Treatment of Pediatric Functional Abdominal Pain
Children with chronic functional abdominal pain frequently experience activity limitation and functional impairment as a consequence of their illness but continued participation in activity is a vital positive predictor of functioning and recovery. However, there is reason to believe that significant individual differences exist in the relationship between pain, affective variables, environmental variables, social support, sleep, and physical activity that may have significant implications for treatment in this population. This project seeks to use ecological momentary assessment and dynamic p-technique factor analysis to develop an idiographic profile of affect, social support, physical activity, sleep, and pain. This profile can then be used clinically within a multidisciplinary care team consisting of a pediatric gastroenterologist, psychologist, and nursing staff to teach patients about the relationships between these variables and the personalized impact of activity and sleep. This information also can then be used to tailor the individual treatment plan. Specifically, the project will provide an effect size estimate and test the initial efficacy of a personalized medicine intervention for pediatric functional abdominal pain.