Role of 5-alpha reductase 2 and androgens in Tourette Syndrome

Role of 5-alpha reductase 2 and androgens in Tourette Syndrome

This study will help elucidate the role of 5α-reductase 2 (5AR2) and androgens in Tourette Syndrome (TS) and obsessive-compulsive disorder (OCD). 5AR2 is the key rate-limiting enzyme in androgen synthesis; the inhibition of 5AR2 elicits therapeutic effects in patients affected by TS and OCD, highlighting a putative new mechanism for the treatment of these conditions.


Completed Project
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Project ID
NFP0070806

Project Administration

Principal Investigator:

Contact Information

Marco Bortolato, Ph.D.
Assistant Research Professor
mbortolato@ku.edu 
785-864-4002
Malott Hall Rm 5064
1251 Wescoe Hall Drive
Lawrence, KS 66045

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