Clusterin (APOJ) in brain mitochondria

Clusterin (APOJ) in brain mitochondria

Clusterin (CLU), also known as apolipoprotein J (APOJ), has recently been highlighted as the third most potent genetic risk factor for late-onset Alzheimer's disease (LOAD); yet little is known about the underlying mechanisms. This project seeks to determine the sub-mitochondrial localization of nCLU and the impact of CLU deficiency on brain mitochondrial respiratory activity.


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KAN0077324

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